What is the adult dose of Diphenhydramine for a dystonic reaction?

What is the adult dose of Diphenhydramine for a dystonic reaction?

• A. 25mg IV
• B. 50mg IV (preferred)
• C. 100mg IM
• D. 50mg PO

Answer: (B)

The adult dose of Diphenhydramine for a dystonic reaction is 50mg IV, which is considered the preferred route for rapid administration in emergency situations. Diphenhydramine, an antihistamine with anticholinergic properties, is effective in counteracting the acute effects of dystonic reactions, often caused by antipsychotic medications. The intravenous route allows for quick absorption and onset of action, which is crucial in managing such reactions promptly. While other routes and dosages exist for Diphenhydramine, such as oral or intramuscular administration, these alternatives can be slower to take effect compared to the intravenous route, making them less ideal in urgent clinical scenarios like dystonic reactions. The intravenous dosage of 50mg is aligned with established protocols for effectively alleviating symptoms and providing immediate relief.

The adult dose of Diphenhydramine for a dystonic reaction is 50mg IV, which is considered the preferred route for rapid administration in emergency situations. Diphenhydramine, an antihistamine with anticholinergic properties, is effective in counteracting the acute effects of dystonic reactions, often caused by antipsychotic medications. The intravenous route allows for quick absorption and onset of action, which is crucial in managing such reactions promptly.

While other routes and dosages exist for Diphenhydramine, such as oral or intramuscular administration, these alternatives can be slower to take effect compared to the intravenous route, making them less ideal in urgent clinical scenarios like dystonic reactions. The intravenous dosage of 50mg is aligned with established protocols for effectively alleviating symptoms and providing immediate relief.